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The Scientific Revelation Behind Rise Of The Planet Of The Apes 3: Analysis Of The Reasons For The High Failure Rate Of New Drug Development For Alzheimer's Disease

Release time:2025-01-13

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In the movie, the conflict between humans and orangutans seems to happen by chance, but in fact, its root cause lies in the irregular operation of new drug experiments.

This point is easily overlooked by everyone, but it may be the key.

The research and development of new drugs generally has strict procedures and is full of difficulties.

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This is the case with drug development for diseases like Alzheimer's disease.

There is no clear conclusion on the cause of Alzheimer's disease, and there are currently many hypotheses, such as the β-amyloid cascade theory and the central cholinergic damage theory.

Enterprises have great difficulties in research and development, and in recent years, relevant drug research in the news has continued to fail.

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In 2006, the Ministry of Science and Technology issued relevant regulations to regulate matters related to experimental animals. This is because experimental animals play a vital role in the drug development process.

Will works in a genetics company to research new drugs to treat Alzheimer's disease. The difficulty of treating this disease has become a major problem in his research process. The reason for his private and irregular operations is precisely based on this background.

Will's behavior seriously violated the process of new drug research and development.

The first generation of new drugs he developed had huge problems.

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In reality, new drugs undergo multiple phases of clinical trials.

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For example, in the early stage, healthy volunteers are selected to determine the safe dosage of the drug, in the mid-term, attention will be paid to its therapeutic effect and possible side effects, and in the later stage, its effects and potential adverse effects will continue to be monitored after the drug is launched.

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Will's new drug was not even approved for clinical trials because, despite a seemingly successful case in primate experiments, he used it on his sick father without permission.

As a result, his father soon developed antibodies and his condition worsened.

He began research on second-generation new drugs. This new drug is more effective, but the side effects are equally worrisome. If you are not careful, inhaling drugs can be life-threatening.

All this stemmed from his desire to cure his father quickly and not complying with the regulations for new drug trials.

Caesar, the ape on the other side, is in pain.

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It was mistreated by the zookeepers, and the conflict between it and humans was further intensified.

Will's second-generation new drug released an aerosol after being retrieved from the zoo, which immediately triggered a series of reactions.

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Many people became sick and died after inhaling it, and it was called "simian flu."

In "Rise of the Planet of the Apes", the flu caused humanity to begin to decline, and human leaders regarded Caesar as the culprit. This behavior made the relationship between orangutans and humans very bad. At first, Caesar just longs for freedom, but as the plot develops, the hatred between the two races gradually deepens.

In this story, the conflict between technology and ethics is highlighted.

Will violated the ethics of technological research and development in order to save his father.

When developing new drugs, strict testing procedures must be followed to ensure the safety and effectiveness of the drugs and to protect consumers, including those who will use these drugs in the future.

Will used drugs without authorization when an experiment failed to meet the standards, and later developed more dangerous drugs.

This is similar to the trend of scientific and technological progress in reality, such as cloning and other cutting-edge technologies, which all need to find a balance between scientific and technological exploration and ethical norms.

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Failure to respect ethical norms in scientific and technological research and development is likely to bring unpredictable disasters.

If we look at the progress of the story, we will find that Rowell followed the norms of drug research and development and did not conduct any unauthorized drug trials.

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Maybe there will be no "simian flu" later.

In scientific research activities, various countries have established standards for drug research and development and rules for experimental animal management. Taking the guidance issued by the Ministry of Science and Technology of my country in 2006 as an example, it aims to reduce the risks caused by non-standard operations and prevent the contempt for life during the scientific research stage. , and prevent possible unexpected unfortunate events.

The events in the film are good material for reflection.

Human beings did not comply with research and development regulations for their own purposes, which eventually led to the outbreak of war.

In real life, people often ignore the importance of complying with regulations in various fields because they are eager for quick success or only value short-term interests.

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In the field of environmental development, some people only pursue economic gains but ignore ecological protection; while in the industrial production process, some people ignore production safety regulations.

We should take this as a lesson and pay attention to behavioral norms while pursuing results.

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So, how do you think we can more effectively coordinate the relationship between interests and norms in the field of work or research?


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